Mage-a4 immtac
WebDec 18, 2024 · Kageyama et al. reported the clinical trial results of a TCR-T therapy targeting the HLA A2402-restricted MAGE-A4 epitope NYKRCFPVI in 10 patients with recurrent … WebDec 6, 2024 · Immunocore announces initial Phase 1 data of ImmTAC® candidate IMC-C103C targeting MAGE-A4 Clinical activity with confirmed durable responses in ovarian …
Mage-a4 immtac
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WebMar 3, 2024 · IMC-C103C, an ImmTAC molecule targeting an HLA-A*02:01 MAGE-A4 antigen, is currently being studied in a first-in-human, Phase 1/2 dose escalation trial in patients with solid tumor cancers including non-small-cell lung cancer (NSCLC), gastric, head and neck, and ovarian. WebMay 23, 2024 · IMC-C103C is an immune mobilizing monoclonal T cell receptor against cancer (ImmTAC ®) designed for the treatment of cancers positive for the tumor …
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WebDec 6, 2024 · Immunocore announces initial Phase 1 data of ImmTAC® candidate IMC-C103C targeting MAGE-A4 Clinical activity with confirmed durable responses in ovarian cancer and a confirmed durable...
WebMay 11, 2024 · Plan to report Phase 1 data from ImmTACclinical candidates targeting PRAME (3Q 2024) and MAGE-A4 (4Q 2024) in multiple solid tumorsthis year Net KIMMTRAK and pre-product revenuesof£10.5million($13.8million)in Q12024andnet cash position of approximately$271 million as of March 31, 2024
WebMar 21, 2024 · An immTAC targeting a MAGE-4 peptide (IMC-C103C) is being investigated for use in malignancies such as upper gastrointestinal, and head and neck cancers, 53 and early phase studies are underway investigating IMC-F106C, an immTAC targeting PRAME, a tumour antigen overexpressed in tumours including squamous cell carcinoma, small … changer la batterie iphone 7WebMay 20, 2024 · IMC-C103C is an ImmTAC being investigated against MAGE-A4, which is among the most commonly expressed cancer testis antigens in solid malignancies, but with minimal to absent expression on normal ... changer la date google earthWebJan 26, 2024 · On December 6, 2024, the company announced initial Phase I data for another of its pipeline products, IMC-C103C, a bispecific T cell engager targeting MAGE-A4 for advanced solid tumors. This drug was developed with Immunocore’s ImmTAC technology platform and in partnership with Genentech, a Roche company. changer la clé wifi orange livebox 5WebThe MAGE-A4 antigen is among the most commonly expressed cancer-testis antigens (expressed in approximately 67% of the synovial sarcomas and 34% of the MRCLS). We … hard wired smoke detector 3 beepsWebIMC-C103C is an ImmTAC being investigated against MAGE-A4, which is among the most commonly expressed cancer testis antigens in solid malignancies, but with minimal to absent expression on normal tissues and/or hematopoietic cells. The most advanced ImmTAC in development, tebentafusp (IMCgp100), directed against melanocyte … changer la clé windowsWebDec 8, 2024 · Immunocore presents ovarian cancer expansion data for ImmTAC® candidate IMC-C103C targeting MAGE-A4 Phase 1 trial enrolled all comers, with vast … changer la clé wifi freeWebDec 8, 2024 · • IMC-C103C (MAGE-A4 × CD3) is an investigational ImmTAC targeting an HLA-A2-presented peptide derived from the intra-cellular cancer testis antigen MAGE-A4 tissue expression • This analysis provides an update to data presented at ESMO-IO 2024 [1], focusing specifically on patients with ovarian cancer (OC) who received doses of IMC … changer la configuration outlook