TīmeklisLAMP5. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. Tīmeklis2024. gada 18. febr. · “In addition to genes that have previously been associated with myeloma, the investigators identified a new gene, LAMP5, that is overexpressed in bone lesions and most likely contributes to disease progression.” This may possibly become a target for future therapies, yet to be developed.

LAMP5 lysosomal associated membrane protein family member 5 …

Tīmeklis15 rindas · 2024. gada 21. marts · LAMP5 (Lysosomal Associated Membrane Protein Family Member 5) is a Protein Coding gene. Diseases associated with LAMP5 … Tīmeklis2024. gada 22. marts · Knockdown of LAMP5 promoted apoptosis in MM cells, but had no effect on the cell cycle. Mechanistically, LAMP5 may exert its pro-tumor effects in MM in part through activation of p38 protein. We screened LAMP5 for the first time as a key gene for MM progression and recurrence, and found that LAMP5 may exert its … timetable black and white

Бәхәс:LAMP5 — Wikipedia

TīmeklisLAMP5 is part of cluster 10 Brain - Neuronal signaling with confidence i Confidence is the fraction of times a gene was assigned to the cluster in repeated clustering, and … TīmeklisLAMP5 depletion significantly inhibited leukemia cell growth in vitro and in vivo. Functional studies showed that LAMP-5 is a novel modulator of innateimmune pathways in MLL-r leukemias. Tīmeklis2016. gada 7. jūn. · LAMP5 deficient mice validate mAb 34.2 anti-LAMP5 antibody specificity. (A) Targeting strategy to generate a LAMP5 deficient mouse line. The targeting vector was designed to remove exons 3–5 after CRE-induced recombination, leading to a null allele. LAMP5 null animals are viable and therefore used for most … parish bathroom shower curtains