Human recombinant erk5

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August undefined, 2024

WebThis MAPK7 (ERK5) recombinant human protein (full length) was expressed in insect cells. MAPK7 (ERK5) serine/threonine kinase is a member of the MAP kinase family and … Web1 dec. 2024 · Erk5 regulates fatty acid oxidation by upregulating the expression of peroxisome proliferator-activated receptor γ co-activator-1α (Pgc-1α) [51], suggesting that Pak2 may regulate mitochondrial...

5598 - Gene ResultMAPK7 mitogen-activated protein kinase 7 [ (human)]

Web15 mei 2009 · One of them, Erk5, has been linked to the proliferation of breast cancer cells in vitro. Here we have investigated the expression and prognostic value of Erk5 in human breast cancer. Methodology/Principal Findings Animal and cellular models were used to study Erk5 expression and function in breast cancer. Web13 apr. 2024 · Pathophysiological Impact of the MEK5/ERK5 Pathway in Oxidative Stress. Previous Article in Journal. Spatiotemporal ... Inducing TGF–β signaling-associated cancer-EMT in A549 and H1299 cells were treated with 20 ng/mL of recombinant human TGF–β1 in RPMI-1640 for 48 h in 37 °C/5% CO 2 conditions. 2.3. Small-Molecule Treatment. ... phool jhari

ERK5 (Ser496) Polyclonal Antibody – Bioss

Web27 sep. 2016 · Extracellular signal-regulated kinase 5 (ERK5, BMK1) is a member of the mitogen-activated protein kinase (MAPK) family, which includes ERK1/2, JNK1/2/3, and p38α/β/δ/γ ( 1 ). However, unlike the other MAPK members, ERK5 contains a unique 400-amino-acid C-terminal domain in addition to the kinase domain. WebView Mouse Monoclonal anti-ERK5/BMK1 Antibody (OTI3H2) [FITC] (NBP2-71243F). Validated Applications: Flow, ICC/IF. Validated Species: Human, Mouse, Rat. ... Full length recombinant protein of human ERK5/BMK1 (NP_002740) produced in HEK293T cells. Isotype: IgG1. Clonality: Monoclonal. Host: Mouse. Gene: MAPK7. Purity: Immunogen … Web10 okt. 2024 · You et al. report the development and characterization of INY-06-061, a potent and highly selective ERK5 degrader. While pharmacological ERK5 degradation did not result in potent anti-proliferative or anti-inflammatory effects in this study, INY-06-061 can serve as a useful chemical probe to further dissect/investigate the biological … how does a dishwasher pack work

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Erk5 participates in neuregulin signal transduction and is ...

Web26 jul. 2024 · Recombinant GST-tagged human Smad1, ... Recombinant Erk5 active or recombinant Erk5 inactive (0.3 μM) were incubated with GST-Smad1(WT and mutants), GST-Smad2(WT), GST-Smad3(WT) or GST-Smurf2(WT and mutants) (1 μM) and 0.5 mM ATP in 30 μl kinase buffer ... Web28 apr. 2014 · ERK5 Regulates Efferocytosis-Related Gene Expression and M1/M2-Type Polarization To investigate the molecular mechanisms by which ERK5 regulates the capacity of phagocytosis and clearance of ACs, we investigated the expression of efferocytosis-related genes. how does a dishwasher use magnetsWebExtracts of HEK 293 cells transfected with recombinant human ERK5/BMK1 were resolved by SDS-PAGE on a 10% Tris-glycine gel and transferred to nitrocellulose. The membrane was blocked with a 4% BSA-TBST buffer overnight at 4oC, then incubated with 0.15-1.5 μg/mL of the ERK5/BMK1 how does a dishwasher mount

"Web31 jan. 2024 · To address the fundamental basis of this unique feature, we generated various ERK5 mutants using a site-directed mutagenesis approach. cDNAs encoding Flag epitope-tagged human ERK5 full length (ERK5-FL), truncated and phospho-mutants, were subsequently integrated into the genome of HeLa cells using the Flp-In T-Rex system to … " - Human recombinant erk5

Human recombinant erk5

Anti-ERK5 (phospho T218 + Y220) antibody (ab5686) Abcam

WebWestern Blot: ERK5/BMK1 Antibody (SD2084) [NBP2-67802] - Analysis of ERK5 on Hela cells lysates using anti-ERK5 antibody at 1/1,000 dilution. Immunocytochemistry/ Immunofluorescence: ERK5/BMK1 Antibody (SD2084) [NBP2-67802] - Staining ERK5 in 293 cells (green). The nuclear counter stain is DAPI (blue). Webwith recombinant human ERK5/BMK1 were resolved on a 10% Tris-glycine gel and transferred to nitrocellulose. Membranes were blocked with 1% BSA, followed by incubation with 0.15-1.5 μg/mL of anti-ERK5/BMK1 antibody, which recognizes the target protein independent of the phosphorylation state. After washing, membranes were incubated with

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WebThese antibodies target ERK5 in Human, Mouse, Rat and Non-human primate samples. Our ERK5 monoclonal, polyclonal and recombinant monoclonal antibodies are … WebDescription The MAPK/ERK signaling pathway is a major participant in the regulation of cell growth and differentiation. It can be activated by various extracellular stimuli including mitogens, growth factors, and cytokines. Upon stimulation, MEK1/2 phosphorylates and activates ERK1/2.

WebMEK5 or MAP2K5 (mitogen-activated protein kinase kinase 5) is a dual specificity protein kinase that belongs to the MAP kinase kinase family which specifically interacts with and … Web13 apr. 2024 · 6SHFLHV5HDFWLYLW\ Human/Mouse 6SHFLILFLW\ Detects human and mouse ERK5/BMK1 in Western blots. 6RXUFH Polyclonal Goat IgG 3XULILFDWLRQ Antigen Affinitypurified ,PPXQRJHQ ( FROLderived recombinant human ERK5/BMK1 Met1Glu432 Accession # Q13164)RUPXODWLRQ Lyophilized from a 0.2 μm filtered …

WebERK5/MAPK7 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5. WebErk5 (D3I5V) Rabbit mAb recognizes endogenous levels of total Erk5 protein. This antibody detects isoforms 1 and 2 of human Erk5 and isoforms 1-3 of murine Erk5 (note multiple bands in western blot image). Species Reactivity: Human, Mouse, Rat, Monkey Species predicted to react based on 100% sequence homology:

WebRecombinant human ERK5 protein (ab126913) Datasheet SDS Submit a review Submit a question References (1) Key features and details Expression system: Baculovirus infected Sf9 cells Purity: > 75% …

WebERK5 MAP kinase cascade has a crucial functions like- induction of special form of cardiac hypertrophy, enhanced neuronal survival and early steps of muscle cell differentiation. … phool investorsWeb9 feb. 2024 · 免疫原： Recombinant protein of human MAP2K5 ... This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). phool instagramWebMonoclonal (1.T218/Y220) Validations: None Available. Applications: WB, IHC and 3 more. Reactivity: Homo sapiens (Human), Mus musculus (House mouse), and Rattus norvegicus (Rat) Phospho-ERK5 (Thr218, Tyr220) Polyclonal Antibody. 44-612G is a primary antibody from Invitrogen Antibodies. how does a dislocated shoulder look likeWeb20 jun. 2006 · ERK5 is expressed in proliferating cortical progenitor cells. (A) Confocal images of ERK5 immunostaining in rat cortex.Control, anti-ERK5 antibody preabsorbed with recombinant ERK5 protein. (B) Western blot analysis of ERK5 expression in rat cortex from E12, to postnatal day (P) 0, to adult. β-Actin was used as a loading control.ERK5 is … phool indiaWeb12 apr. 2024 · The MEK5-ERK5 pathway regulates cancer cell proliferation and survival, and ERK5 inhibitors have shown anticancer activity in preclinical models of solid tumors. how does a dishwasher use heat energyWebRecombinant fragment corresponding to Human ERK5 aa 550-800. (N-terminal His-tag and GST-tag; Expressed in E.coli). Database link: Q13164 Run BLAST with Run BLAST … how does a dishwashing machine workWeb15 feb. 2015 · Radioactivity incorporated into the recombinant protein was quantified after SDS-PAGE by PhosphoImager analysis. ... Therefore, these findings are highly relevant because elevated MEK5/ERK5 expression in human epithelial tumors correlates with unfavorable prognosis . In addition, inflammation is a hallmark of most, if not all, ... phool incense uk