Cisplatin and breast cancer

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August undefined, 2024

WebJun 15, 2024 · Introduction. As one of the main causes of female deaths, breast cancer (BC) is a heterogeneous tumor with different subtypes [1,2].Triple negative breast …

Gemcitabine Plus Cisplatin in Breast Cancer - Cancer Network

WebNov 13, 2013 · Cisplatin and paclitaxel are active in triple-negative breast cancer (TNBC). Despite different mechanisms of action, effective predictive biomarkers to preferentially inform drug selection have not been identified. WebJul 22, 2024 · Cisplatin represents a promising chemotherapeutic compound in neoadjuvant approaches and in the metastatic setting, but its use is limited by scarce bioavailability, severe systemic side effects and drug resistance. Novel site-directed aptamer-based nanotherapeutics have the potential to overcome obstacles of chemotherapy. kent ohio calendar of events

Collagen 1A1 (COL1A1) promotes metastasis of breast cancer and …

WebApr 13, 2024 · Increasing WNT7A synthesis by invasive cancer cells in breast cancer may improve TGF ... Polanska HH, Vaculovic T, et al. Sensitivity to cisplatin in head and … WebApr 1, 1993 · Pharmacological studies on breast cancer can be cited to Cisplatin [12] .Cisplatin is one of the factors used in chemotherapy; and yet, it is not always used to … WebJan 6, 2024 · Cisplatin with veliparib or placebo in metastatic triple-negative breast cancer and BRCA mutation-associated breast cancer (S1416): a randomised, double-blind, … kent ohio city council meeting

Metformin overcomes resistance to cisplatin in triple-negative …

Cisplatin LBBC

WebMany drugs used to treat breast cancer, including taxanes (docetaxel, paclitaxel, and protein-bound paclitaxel), platinum agents (carboplatin, cisplatin), vinorelbine, eribulin, … WebHere we aim to study the effect of cisplatin at different doses on breast cancer growth and metastasis. Methods: We used cisplatin to treat breast cancer cells, then detected the … is indentured servants a type of slaveryWebCisplatin With or Without Veliparib in Treating Patients With Recurrent or Metastatic Triple-Negative and/or BRCA Mutation-Associated Breast Cancer With or Without Brain Metastases The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. is independence required for a compilation

"WebMay 26, 2024 · Neither gemcitabine nor cisplatin affected berzosertib PK. Most patients in both arms achieved a best response of either partial response or stable disease. ... E. R. Triple-negative breast cancer ... " - Cisplatin and breast cancer

Cisplatin and breast cancer

WebCisplatin is a chemotherapy drug. You might have it as a treatment for a number of different types of cancer. You might have cisplatin on its own or in combination with other … WebMar 30, 2024 · It is important for breast cancer patients on cisplatin to avoid consuming foods or taking supplements that will lessen the cytotoxic impact of this drug (and any other drugs in the chemotherapy regimen) on cancer cells. Note that compounds that provide relief from chemotherapy side effects might also provide some protection to breast …

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WebMar 22, 2024 · The addition of rucaparib to cisplatin did not increase 2-year DFS (54.2% cisplatin vs. 64.1% cisplatin + rucaparib; P = 0.29). ... Patients with triple-negative breast cancer (TNBC) who have ... WebJan 1, 2024 · Conclusion: Thus, cisplatin prevents breast cancer metastasis through blocking early EMT, and the combination of cisplatin and paclitaxel represents a …

WebIn patients with breast cancer, cellular expression of COL1A1 was associated with ER/PR expression and metastasis status. The increased COL1A1 level was associated with poor survival, especially in patients with ER+ breast cancer. Patients with a high-level of COL1A1 showed better cisplatin-based chemotherapy response. WebJan 24, 2024 · Background Shenqi Fuzheng injection (SQFZ) combined with chemotherapy can sensitize tumour cells. However, the mechanisms underlying SQFZ’s effects remain unknown. In human breast cancer cell lines and M2 macrophages, we showed that SQFZ was a significantly potent agent of sensitization. Methods The human breast cancer cell …

WebApr 12, 2024 · The long-term prognosis for women with recurrent endometrial cancer is also poor. The combination of the chemotherapy drugs cisplatin and paclitaxel has long been … WebOct 22, 2024 · Background Chemotherapy is a standard therapeutic regimen to treat triple-negative breast cancer (TNBC); however, chemotherapy alone does not result in …

Web2 days ago · Testicular cancer, also known as testicular germ cell tumors (TGCT), is the most common type of cancer in young men. When treated with cisplatin, the tumor cells stop growing and die. This is ...

WebFeb 1, 2001 · To date, three clinical trials combining cisplatin with gemcitabinein advanced breast cancer have been reported (Table 3). [42-44] Hematologic toxicity has been the … is indenting paragraphs necessary in booksWeb17 hours ago · Injectable cisplatin, methotrexate, and fluorouracil These generic drugs are widely used to treat common cancers in adults and children. Methotrexate treats acute lymphoblastic leukemia in... is independent co uk a reliable news sourceWebApr 13, 2024 · Increasing WNT7A synthesis by invasive cancer cells in breast cancer may improve TGF ... Polanska HH, Vaculovic T, et al. Sensitivity to cisplatin in head and neck cancer cells is significantly ... is independence pass open todayWebApr 12, 2024 · The long-term prognosis for women with recurrent endometrial cancer is also poor. The combination of the chemotherapy drugs cisplatin and paclitaxel has long been the standard treatment for women with advanced or recurrent endometrial cancer. But treatment options for these two groups of patients have changed recently, largely … is independent a adjectiveWebFeb 1, 2011 · The previous phase II study showed that gemcitabine and cisplatin combination (GP) is an effective regimen in triple negative breast cancer (TNBC). The potential therapeutic effects of GP in advanced TNBC deserve further evaluation yet. Eligible patients are randomly assigned to receive either GP or GT regimen to verify the … kent ohio clerk of courtsWebMar 17, 2015 · Compared with carboplatin, cisplatin has shown superior efficacy in the neoadjuvant setting of locally advanced triple-negative breast cancer, with a higher proportion of patients achieving a pathological complete response and a significant improvement in overall survival. kent ohio coffee roastersWebMar 2, 2024 · Breast cancer is the most common cancer worldwide in women, accounting for ~24.2% of all female cancer incidence and 15% of cancer-related deaths [].Depending on the expression status of the ... kent ohio court records